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Mechanism of action, characteristics and use of THPS

The full name of THPS is Tetrakis(hydroxymethyl)phosphonium sulfate, CAS No. is 55566-30-8, which has its own characteristics in terms of bactericidal effect, environmental protection characteristics, application, price, solubility and so on. Tetrakis(hydroxymethyl)phosphine sulfate(THPS) is used in aquaculture water treatment, garbage deodorization, indoor sterilization, oil field mining and other industries, but the use is very wide, and the effect is also very significant.


The use of description

1, inhibit microorganisms, industrial cooling water system in the microbial reproduction control effect is very good. For indoor sterilization, inhibit the growth of bacteria and fungi and other microorganisms agreed to have a good effect.

2, flame retardant, widely used in cotton and leather flame retardant, flame retardant effect is good.

3, aquatic bottom reform effect is obvious. Tetrakis(hydroxymethyl)phosphonium sulfate is a classic bottom improvement product in aquaculture. It can effectively degrade the water body ammonia nitrogen, nitrite, hydrogen sulfide and heavy metals and other toxic substances, decompose the bottom of the pool deposited residual bait, feces, plants and animals and algae dead bodies and other organic waste and other harmful substances. It can completely eliminate the corruption phenomena such as blackening of bottom mud, heat, odor, fishy acid, etc. It can effectively degrade algae toxicity and other biological toxins. Remove the fishy odor of the water body and the bottom of the pool, decompose the viscous material of the water body, effectively regulate the dissolved oxygen, temperature, bottom heat, nutrient salts and other undesirable vertical stratification phenomenon. Tetrakis(hydroxymethyl)phosphonium sulfate on the bottom of the plankton type pond, saline type pond bottom and fishy odor and other aging ponds, improve water transparency, to ensure that the normal photosynthesis of the plankton, deodorization effect is significant; especially suitable for sudden changes in water quality, poor climate and morbidity during the improvement of the substrate can significantly improve the ability of the aquatic animals to resist stress.

4, Bactericidal effect, for oilfield mining and water treatment. Its phosphorus atoms have three oxidation states, and we all know that phosphorus can also have five oxidation states, so it has the ability to kill life quickly.


Mechanism of action

Tetrakis(hydroxymethyl)phosphorus sulfate has a complex mechanism of bactericidal action, and the current research conclusions are as follows. It is only one carbon atom long, which means it does not cause invertible foam and there is no interface or substrate. Quaternary phosphates are positively charged and can be selectively adsorbed by negatively charged bacteria, enter the cell membrane through penetration across the bacterial surface, impede the semi-permeability of the cell membrane, and further enter the cell interior, so that the cellular enzymes are blunted, the protein enzymes can not be produced, thereby denaturing proteins to achieve the role of killing bacterial cells. Its lipophilic group can dissolve and damage the fat wall on the cell surface, change the physical and chemical properties of the cell protoplasmic membrane, and the death of bacteria.


Product characteristics

1, good effect of mixing and compounding. Tetrakis(hydroxymethyl)phosphonium sulfate can be mixed and matched with most of other oilfield auxiliaries. The effect of boiling and compounding is very good. After compounding, it does not affect the effect and performance of the product. For example, with a small amount of quaternary ammonium surfactant formulation products can ship very good results.

2, tetrakis(hydroxymethyl)phosphonium sulfate has the characteristics of high efficiency, broad-spectrum, low toxicity, low dose, low foaming, environmentally friendly and so on. It is a new type of internationally recognized bactericide, with strong killing effect on bacteria and algae.

3, bactericidal and efficient, in the oilfield and water treatment industry with excellent bactericidal effect. In the United States, the Middle East, Europe. Southeast Asia and other oil fields in the extraction process is very effective, in the marine oil exploration is also a large number of applications.

4, green environmental protection. No secondary pollution after use. There is no residue. The water quality, soil, air are not formed secondary pollution. Can be degraded to green harmless products.

5, the price is cheap, the price once reached a record high, and now back to the cost line near. Compared with other fungicides, the price has a greater advantage, and the effect also has its own characteristics.

6, tetrakis(hydroxymethyl)phosphonium sulfate has good water solubility, low freezing point, stable chemical properties, and long time storage does not affect its quality.


Tetrakis(hydroxymethyl)phosphonium sulfate is a very new biocide, which was first mass-produced as a precursor of flame retardant for dealing with cotton fiber products such as overalls. It was used in the UK as an effective biocide in cooling systems. Later, tetrakis(hydroxymethyl)phosphine sulfate was applied to oilfield water systems, and its exceptional effectiveness against sulfate-reducing bacteria made it the biocide of choice when there was H2S generation or inhibition of corrosion caused by sulfate-reducing bacteria.


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